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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '450229ca0fec94e5735ee7ea25e7750b4b3a54eb4848dfdbd6723e37c92378b3' 
  AND token = 'cPJpAuaE9No0oXLYRAsASMAgJqa0W7eJ1rJtwlky1Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}