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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd0e8e49d0a59deb8d380957c259a6e3eb5e948b768b7a936faf4fb29c49e3494' 
  AND token = 'K1YczzpWAhfsCtECDhW6tx6fxY1qiKa3zSKdUKH58hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}