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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '15f8b416f16481752b5bc2829d1c612e7cca38678e23a09620cb106a00c6318e' 
  AND token = 'GyFWD59csTI4TZstRgPnbDec/awwquIHBnmCMBZwCHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}