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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '08d62161eee1bf6390b2045fe5e327c64159b0036a85f5d226b14079f12e6b91' 
  AND token = 'U8uxom/I7/RHivOz53IH6IQLck2uao7cpLkA0VYvFkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}