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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7f80711802d6ea56c01407ffa2c046c9c4ed4cf36c344a4b1ed983834806025a' 
  AND token = '548RxqBQqmM+L+8iSuhOw71bzJawdOK6k08Quq9O/So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}