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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '78b4d3bdd37d912bf9dc38dd3cbad8fd3fd3a93ff5ca6a9ae36cd814494e29bb' 
  AND token = 'qxp6LkWNiPy1ncaoFw3ykubhtJ54BXmxA0pAIVnhxBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}