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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'bc65117afec83bae4a32bb4e93b7864bce32cb673f97fc153212f27c7bc48862' 
  AND token = '8TQo7zO5zN2TZl9/9I//FW9As5Gfw3GwBIMpRWTXktI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}