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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '97e197bf36f15e7b20725af48d08548213c818911f19f01cdccdcb03f1fcb442' 
  AND token = 'CaSMyI+eDYFr2ydCwo5K/GTtGUHsb2rW6BNnn6wxvTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}