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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8f503c3f81830140e28dadc1b5cb4b750522677b891abd5b33064f95a89f10aa' 
  AND token = 'XVCUuY2DhROYZccYo7XZXe0Bf9XnpnRlzerAp0DE/oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}