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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1a0718e500136adfa97b4d9c74b591a13cd87a2bcb7e732c5fda391b9a9e4604' 
  AND token = 'La+E+Js1/C/nKjBOgFoe1S5vXdBrFBoS/x3hxcARP7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}