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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b1c253e19cacfe208911bc4cbd29403ee9925b7383a8a1e7d19047be66726624' 
  AND token = 'S4eW++r4YBDLVn7ipv0oDuBN+us7p2o6Qz7ZWTrEvOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}