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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '289352e5e1df645fb6cc8e4522cbb41f460241b8f0ce700e3cdda0363cb77707' 
  AND token = 'dTMaZtDZNv6pIVzHqtekvd7oPjPynK1YDNFZj2Z9MX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}