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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a5278b7b0df653743f4d380515cb66127674b4a6060c8fab72fffd47a090a037' 
  AND token = 'k01o5/l3upUfWxoBks9JJDc26uJD5G1rbTizhkxhlyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}