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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '21b16cda4cf0339f4ec9c2ce99b6ee814acbd2ebb0e0285466872b56202a128d' 
  AND token = 'MHzHVDto2AZgI8k7l/0Qc1GgnRfAux6YaohANymhq98=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}