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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '451dc825c1c75194bef5e33b110cdcea476e02bfced0a9fd20646ffe50f9b743' 
  AND token = '4ERfKQ62HGBoIcCyWLloOP3WYsPkxLc5A3uKp8yXL5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}