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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f8d3848f9a7a77fc7078314173f5fecc48d84047de184972fb49d1dc94e65d54' 
  AND token = '+o9HT1QKcHLBhFPSOwovSIvhp327TlI14uxE4mT7RCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}