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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1366a7ddcf606e5791e59756ad18bb6a44ee666c063601bd16227e2e1e604222' 
  AND token = '71ohToZJefqPG5fxAUA/mnOvIQsoAUveEOy2y5oHk1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}