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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '294b7b19278a7e165da9fe9381b133b4b91891520a62617f64df05fed3450c21' 
  AND token = 'YxhFY3pwtmG/yeY9bBLqbeOhusdxds+eknn1fi3notU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}