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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1289ba177f2233e3e69a72401816b4074787777029ffeddd1b4cfc957f2ee505' 
  AND token = 'VS6T53f0/lKwAFHtSQoTdmC5FT8epig68brHQDbXhf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}