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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '15bd54208be71fa5b4892bcce979779ed750d0d3583e004f952bb9f880345307' 
  AND token = 'zohtXV+kzamrVt37A7SYutYRf6gjpJs7O45f6MLsHDk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}