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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b6e82252d2235b29e1b9fce73adad24f4f8b493a895693b38f0ab8e33efaf9e8' 
  AND token = '/8oyO1bL/Ajs0x6Jg21+yzIyF61rHDhQ7uTBKA5tpbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}