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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a1ff506296605320294490e887c62bfc7b59e069962db9e90a139f8de0b49d8' 
  AND token = 'OhLzIMPB8xf0bxW/u9JAMr8lw90QH9XC08QwBbtXoTY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}