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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3b54f21d3c955da4e7a272ac28b1daed14cfc449f4d68a2d99d56d002af58119' 
  AND token = 'k6xOJFJY6smMvbHepAVbbmxSMg+aubsUD8tctsEUKDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}