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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0504bc4954641c386942844543905856bca995e1b1d991d5c0bc0e626282bd6d' 
  AND token = 'kwAX86PxIc1v/1IyvtehqkWmXJRQGrrGxvdiveM2k7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}