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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '59e3d008432e11de67b3f4adce7b9d69d1eee058bc189b9ff35c6579c987cb19' 
  AND token = 'rLJtbCgtZl2qBPv6Wd3uAiaH4yH6vcxk4/VXsCjXe6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}