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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '458f0f3d04da2b1762431204ce6192583d6dbfb5135bda189595a58c9be5e1d7' 
  AND token = 'RL4u8ZR7rCizxCfN+xpyh2hzv81QA8gQfXlxeGvtu2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}