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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e2550e6ad9eb15cf29976a2b2ed9c0a5113a20ffb75557ca7b9f410cedd2f049' 
  AND token = '2cw3iTN3VaRvZuc8j/8qJypO1QWl05+VCmxpvZG0VVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}