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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7ad2b0ca36635ccebce51fc216d88db62c4e90451959b079d65d62a675a62174' 
  AND token = '2sUvNd0b5FsNX1VyBpbwXdTwl4LPrWMjFUlk/u3vzxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}