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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '004f41421158dc9393f58162bd10787eba3840481d4b8ae98eca63b606ee1dcd' 
  AND token = '4r0vwaeAf9seVG/drRI315cszEajEqMtzbEmYro0JEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}