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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ffd7dcc6abee8201404bc5511844776d67740b46fdcc040d4c528a4cb072f6d7' 
  AND token = 'M28OktzvKn5guBoDv0AYdqs4ie6hSqBRpeRgCNux0TY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}