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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aaa273afd3a574e6575a1ce935208de93e95aed667a60e7b56f262e7f3b82d56' 
  AND token = 'MBZ1ZWy6z/Gp/pawOg1K0RdC1Y6HFKw16Q/PI4BdiTQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}