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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0408bde0d7bc662c8507ecbc851a18b5e45e2e74b1937971a59aa4a0ed7f7388' 
  AND token = '39TdWyDh+Ji8XvHLO2U7GnDMiE2HHmZpAXYhgi+I4C0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}