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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '3a81146dda0c9b897fe7d4eaeff1c5045600fc432b1f08f444fcdc15a024443a' 
  AND token = '0RV40kllDKY8CgC3q++fCbgmA4yxsfznOPV0YdhgFh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}