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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd66f95f5b789f4fe9bc021d03fc291faca0a299096ddb434575df13ca94bcf2c' 
  AND token = 'MNx9jRxppz2P3TqkP6EupSiy5eJdStp1pWQxgXRZ8aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}