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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed878ce4bc21b8bcc4efb35434b407de40a43da987bb58ebcd3898c9af489559' 
  AND token = 'MaD9w+EHLQFfP3dxM7cmUKuRIf5gS8ao0wwQsoU81aM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}