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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e21642c07e780b33462bbe2cf5179ffb7730d21a2431d052896220f673f54a81' 
  AND token = 'MusiTUzF3f3atPMkfg5kMTbiGS1+iKGvI9gAY1RfJ2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}