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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '42dfae5b56ec017673801eaae8e3d0f92615050685f8c7019554d00251c56fe0' 
  AND token = 'ZWei0BZQRFrDuS26jE4lJ0LL94zgPXiWuSO/UBnUo7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}