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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e4a201bfa1f21314fdb630047bbc5c9c6ad9d675427a96687f02176bcbe6f95' 
  AND token = 'oPDS9Mx8tGBN50EU6XiwXFiuRWuZH6PPBYnFprGDx3s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}