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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '335fa2e565130562c73edb09fb5dd4e2cddcb28b64430365aa24b421701deeda' 
  AND token = 'P2k/sVESzlY2/wMuX6dbjIITqBArjBSrSbCq4rFozc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}