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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '212428610cdc55bb9488adbc1cdadbe6c6fbf5f79558e922a06e97a8bc82bc7b' 
  AND token = 'B4uzk6FnmhW3EMNyTGFmUg49dKpxz1kRrsFQfg2Yalo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}