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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7e189e85371d648a7858f6cb238469a447dc5b2cc7847031ece77ee882394a3e' 
  AND token = '52mY0lYnoOGMdMW6nnnHXh7oNJbq6OKeObeOfGaNdag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}