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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b0f6d37fc405df6e3876e4f652571e77ed36a0737cf241c50901d4fb4dadb517' 
  AND token = '9xTNwPJqM0wmlu3ZZGemu6NzSuP3qbBOGMDtneb7qS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}