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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1581fac8cfd58aa8ed7e07521e6a2e21e85f37a19cb5d25ed51b3f25d0e46516' 
  AND token = 'ilbY6zDvXoFOFDCdbLfceVLoLgNRKXNW26GH4yWuVyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}