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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '589cbf3861ab52332d455e0d2817fd0de21b6ab5183e6ccf51a5b093c7a242cb' 
  AND token = '29skLFHhvBRyVX+A8xbAdmA44SNy0N3u0HFJ73d6iO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}