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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a221248f96f850dedc3ef80b8bc1dbd248755155aca36f8a67c3c1f612e42d2e' 
  AND token = 'Et/tLUiii44gawOgczMU1MQE2JdV9zx54M2um/XQ1jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}