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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4fde8171c5b3ba04f6358351919f30a64ff3110943393162301c044d83f3c382' 
  AND token = 'CsO2Frt1cjG8ZenWTdD/FUQytaEddX4R8Gn0upbf2WE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}