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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '79785663d5761f7e025f3fa254b9a3eaadfb590e9db1d72c9109c89b8f7920ca' 
  AND token = 'G9okQtyY+XEIVew3dBo5nr3h4CDAfnTnEMJeGTgHtXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}