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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '666a7726bd2961a094e4c84b880b0f2b93093cb2a2a0802e8bd0d00c6a84786f' 
  AND token = 'u3oyW2zYjxlscuNjERqN16Ms6HPfGeJ6wVpsmCZcI8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}