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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b741ebea04a7d71364aae4eaa17df452fbe29dede4e769dfb918e7da681394d3' 
  AND token = 'fjHVRusw+3HocJHol/lw1bRU6PKDoBQ2K0ZXaj+cTpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}