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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'dd07f08adedecec2433a9bf76856219011fee17c6352c73f8a8173623740b577' 
  AND token = '8B2JDapsJY3NFSpBtL8LVt+Ycp34PB7nkphuQuiV9tg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}